Adenovirus hexon. Sequence comparison of subgroup C serotypes 2 and 5.
نویسندگان
چکیده
منابع مشابه
Adenovirus hexon. Sequence comparison of subgroup C serotypes 2 and 5.
The group C adenoviruses type 2 (Ad2) and type 5 (Ad5) are distinguished serologically by the antigenic determinants of the hexon and fiber capsomers . The hexon-coding region of the viral genome (map units 51.6-59.7) can be divided into three major zones with regard to DNA sequence homology between Ad2 and Ad5 on the basis of fine structure disclosed by restriction endonuclease site mapping ( ...
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We have determined a 139-base-pair sequence of adenovirus 2 DNA that is located immediately leftwards of the cleavage site for endonuclease Sma I at position 51.1. The established sequence includes the hexon AUG initiator codon, located 75--77 nucleotides leftwards of this cleavage site, and codons for the first 26 amino acids of the hexon polypeptide. By the use of purified hexon mRNA as a tem...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1984
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)82161-9